Cancer Immunotherapy Treatment in India

Consult with Dr. Vikesh Shah MBBS, MD (AIIMS, New Delhi)

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Cancer is thought to be the greatest cause of death all over the globe. Methods have been developed with time for the treatment of cancer. Surgery, chemotherapy, and radiation were the traditional ways, but all those have their limits. These treatments might help various forms of cancer, though it presents side effects that are pretty harsh, and the treatments might not target the exact cancer cell always. However, over the years, a new century has emerged regarding treatment for the disease known as cancer-while using the same body, a very crucial immunization, for fighting back this disease. There has been this revolutionary approach toward Cancer Immunotherapy in oncology and practice oncology now.

Cancer immunotherapy is one of the most popular treatments in countries like India, where the healthcare system is rapidly being developed. Excellent medical facilities, top oncologists like Dr. Vikesh Shah, and state-of-the-art technology have made it a destination for many medical tourists seeking cancer treatment.

What is Cancer Immunotherapy?

This is an anticancer therapy aimed at boosting or restoring the patient’s immune function against the illness, as compared to the attack of the neoplasm with the help of traditional methods used in chemotherapy and radiation. Cancer immunotherapy is a kind of treatment that trains the body to recognize and defeat cancerous cells.

Normally, the immune system is designed to detect abnormal cells, which include cancerous cells. Under normal conditions, it is supposed to eradicate them. The cancerous cells, however, find a way to escape the immune system’s detection. Some of the effects include uncontrolled tumor growth and metastasis into other parts of the body. The mechanism devised here in cancer immunotherapy is designed to target such mechanisms, and it makes the immune system detect and destroy the cancerous cells.

There are different types of cancer immunotherapies, and how each of them works is different. They include:

Monoclonal Antibodies: A synthetic molecule artificially developed in the lab, these were designed to serve like the ability of the human immune system’s natural ability of combating harmful aggressors. There are monoclonal antibodies, engineered so they bind only the specific markers to the cancerous cells, this way, their death is promoted as the immune system will kill the cancerous cell. Some monoclonal antibodies even allow delivering drugs to the cancer cells directly.

Immune checkpoint inhibitors: The drugs stop the cancer cells from evading the immune system. Checkpoint proteins inside the cancer cells restrain the activities of the immune system. When these proteins are blocked by the immune checkpoint inhibitors, the brakes for the immune system are removed in order to attack and kill the cancer cells.

Unlike the conventional vaccines, these vaccines prevent existing diseases through stimulation of the immune system against the pre-existence of cancer cells. The usual action in most vaccines takes place when certain proteins or antigens specific to the structural feature of cancer cells are targeted by the immune system.

T-Cell Therapy: This treatment fortifies the immune cells, especially T-cells, that may be able to recognize and kill cancer cells. In some therapies, T-cells are engineered in a lab to be much better at recognizing cancer cells before they are injected back into the body. That is called CAR T-cell therapy.

It is very effective for highly resistant forms of cancers that would not have any other responses-melanoma, NSCLC, leukemia, and lymphomas.

Why is Cancer Immunotherapy Treatment in India So Trendy?

India is one of the favorite destinations for cancer immunotherapy treatment, where patients not only come from the rest of the nation but also from outside the country. This boom in recent times for cancer immunotherapy medical tourism in India can be traced to several reasons.

  1. World-class technology and infrastructure

All these advanced medical institutes scattered across the country carry out the latest technology for cancer diagnosis and treatment. All these hospitals and clinics scattered across the country fulfill the best promising treatments against cancer, including immunotherapy. The world-class hospitals in the country are able to provide the most advanced therapies, which include the immune checkpoint inhibitors, CAR T-cell therapy, and personalized immunotherapy.

Indian healthcare has increasingly been tied up with the major pharmaceutical companies around the world. Hence, the most advanced immunotherapy drugs and treatments available worldwide are now offered to the patients in India. The treatment is generally on a par with the one given in the West but at a fraction of the cost.

Besides, the fast-evolving healthcare systems besides pharmaceutical MNCs running Indian hospitals at par with contemporary discoveries on curing cancer have further made it a list of most potential destinations for the patients with these diseases to enjoy the high quality, low-cost treatment called cancer immunotherapy.

  1. Cost effectiveness of Cancer Immunotherapy in India

Maybe one of the reasons for choosing cancer care in India as a destination is its relatively lesser cost. Some of the Western countries get really expensive. For instance, the newer kinds of therapies-cancer immunotherapies that involve immune checkpoint inhibitors and CAR T-cell therapy-cost hundreds and thousands of pounds in some countries like the USA or UK. Even a session from an immunotherapy can go up to 10,000 to 50,000 bucks.

That will cost just a fraction of this in India. So, the cost of immunotherapy in India is between ₹1 lakh and ₹1.5 lakh. That means roughly $1,200 to $1,800, so pretty affordable for both local and international patients.

Quality over cost will not be compromised over the cost. The hospitals of India maintain international medical standards in treating immunotherapy so that world-class treatment reaches the patients at a lower price.

  1. Medical Research and Clinical Trials

India is also a center of medical research, and many facilities for clinical trails exist. Actually, with its development of drugs and treatments used for cancer immunotherapy, India continues to attract growing numbers of its population for many kinds of experimental therapy trials that people in the region might not access otherwise, so do all possible news regarding therapies against cancer treatment.

This also facilitates the development of future research on cancer; in the long run, hopefully, finding the latest available immunotherapy to cure thousands around the world.

In the process of advanced treatment, they are, in fact, contributing to the inclusion of the global effort to combat this cancer.

  1. Care of Patients through Holistic Treatment

The hospitals of India are not just medication; they are a holistic service for the cancer patient. Hospital services in India are available for international patients, like visa assistance, travel arrangements, translation services, and personalized care plans, to make the whole journey of treatment easy to manage for foreign patients.

Apart from these, Indian hospitals also provide aftercare services such as rehabilitation and counseling. That is, the patient is kept at a good quality of life both during and after treatment. Such all-around care in the physical as well as the emotional sphere is necessary for cancer patients.

How Does Cancer Immunotherapy Work?

Immunotherapy is a new and highly effective treatment for cancer. To understand why immunotherapy is so important, let’s break down how it works.

Role of the Immune System

The immune system is the body’s natural defense. They detect abnormal cells, of which may include viruses, or mutated cells that may become some form of cancer. The immune system partly avoids these cancer cells because it can hide them or the composition of specific proteins that repel an immune response.

Cancer immunotherapy is defined as an improvement or reestablishment of the immunity’s capacity to identify and kill cancer cells. One of the examples that are given include monoclonal antibodies, which can be termed as “shepherds” guiding the immunity towards the cancer cells because they bind with specific markers found on the cancer cells. Once identified by the immunity, it can then focus its resources on destroying such cancer cells.

Checkpoint Inhibitors: Cancer cells produce checkpoint proteins that dampen the immune response and thus evade destruction. Checkpoint inhibitors blockade the action of these proteins and thus effectively ‘remove the brakes’ on the immune system. This allows T-cells, the killer cells of the immune system, to conduct ‘immunologic destruction’ against cancer cells.

Cancer vaccines: These vaccines aim to stimulate the body’s immune system for the recognition of cancer-specific antigens. Hence, targeting these markers, the vaccine promotes the destruction of existing cells, which means prevention of recurrence.

T-Cell Therapy: This treatment makes the patient’s T-cells strong enough so that the latter can more easily recognize and destroy the cancer cells. In some cases, T-cells are genetically modified in a laboratory to make them better at fighting cancer before the engineered T-cells are infused back into the body.

Cancers Treated with Immunotherapy

Immunotherapy has been used to treat many cancers, among them include:

Melanoma: Recently, immunotherapy has been applied in treating melanoma, which is one of the carcinomas of the skin, using the agents pembrolizumab or Keytruda.

Lung Cancer: Needless to say, immunotherapy has great potential applications in NSCLC. Therefore, survival might be increased and recurrence can be minimally low.

In blood cancers like leukemia and lymphoma, agents, including CAR T-cell therapy, can now treat this disease, owing to immunotherapy.

In fact, immunotherapy is an invaluable alternative modality in the treatment of patients with chemotherapy-refractory advanced bladder cancer.

Future of Cancer Immunotherapy in India

The future of cancer immunotherapy in India is bright. As research in medicine progresses and more therapies are developed, India will become a world leader in the treatment of cancer. Personalized immunotherapy in cancer care-treatment tailored to the genetic makeup of the patient-is perhaps one of the most exciting frontiers.

India will embark on international clinical trials, and it will join multi-national pharmaceuticals around the world so that all patients within this country are given the new types of cancer treatment. As nowadays, more forms of immunotherapy are being supplied, the near future for patients having cancer is highly promising all around India.

Conclusion

This is radically new cancer immunotherapy treatment, which is radically altering the very paradigm of treating cancer and promising new hope to many forms of cancer patients. It promises an approach that will make the immune system work against the very enemy: cancer, and opens up new possibilities in therapy to many types of cancerous diseases. It is affordable because of India’s class medical facilities and well-educated oncologists, which is why it is one of the best destinations in the world.

The treatment options in India help the cancer patient in getting the most advanced therapy from expert care along with the total support mechanism which addresses their entire health requirement. Further breakthroughs in medical research and personalization in treatment plans make the future of cancer immunotherapy in India nothing short of a ray of hope.

In case you or some of your dearest suffer from this disease cancer, then it would surely afford the best options of survival after treatments taken in India. Since this would be under the leadership routes of specialists like them that are to lead India towards a novel generation of the era of Cancer Care that’s full of Hope and Healing with better quality life for patients on this earth.