Stage 4 Cancer Treatment in India

Consult with Dr. Vikesh Shah MBBS, MD (AIIMS, New Delhi)

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What is Stage 4 Cancer?

At this stage, the cancer cells have spread from where they first started to other parts of the body. It can be termed as metastatic cancer in this instance. The metastatic cancer might be diagnosed years after there has been an original diagnosis and/or even years after the primary cancer has been dealt with or removed.

A cancer that has spread to another site in the body is still named for its primary site. Thus, metastatic cancer to the brain is, at the bottom, still breast cancer—not brain cancer. In general, stage 4 cancers also have subclassifications that would be either 4A or 4B. Often, this indicates the degree of cancer spread in the body.

Liquid cancers or, more commonly, blood cancers including leukemia, lymphoma, or multiple myeloma, are staged differently than the rest of cancer in most cases because they do not always create tumors. Liquid cancers can be staged based on a variety of different factors that include:

  1. The ratio of healthy normal cells in the blood to diseased cancerous cells
  2. For instance, how much the lymph nodes, the liver, or the spleen may have expanded.

Understanding Stage 4 Cancer Treatment in India

This stage is the final and most advanced level of cancer. At stage 4, the cancer cells break away from the main tumor and travel through either the blood or the lymph system to several parts of the body, where they start forming new tumors far away from the original site of the cancer. This type of cancer is known as metastatic cancer.

. Generally, the treatment of stage IV cancer can be complex and condition-specific as it may depend on the specific cancer, its progression, the medical health of the patient, or other responses.

This includes stage 4 cancer, and by definition, it is typically incurable. However, much treatment does exist to delay progression, and symptom relief can be maximized as much as possible. Further advances in medical science have also introduced new therapies that increase life expectancy and quality greatly.

The most common types of stage 4 cancers that people seem to suffer from include:

Any organ or tissue could have stage 4 cancer, though the most common cancers at this stage include the following:

Stage 4 Breast Cancer: This is when the cancer refers to the spread of the cancerous cells beyond the breast and lymph nodes as well as nearby tissues into other parts of the body such as bones, liver, lungs, and brain.

Stage IV Lung Cancer: At this stage, the spread of cancer is wide to other body parts such as the adrenal gland, bones, and brain.

Stage IV Prostate Cancer: In this case, prostate cancer spreads to bones, lungs, liver, and all other parts of the body.

Stage 4 Colorectal Cancer: In this case, the colorectal cancer would invade the liver, lungs, and distant other organs such that it perfectly affects the treatment.

Staging and grading for stage 4 cancer

Many cancers are staged using a version of the TNM system. In some cases, doctors may rely on the TNM system to establish more information about the spread of certain cancers in each stage. 

The TNM system isn’t used to stage all types of cancer. Some cancers, especially blood cancers, use different staging methods. For example, types of leukemia are often staged using systems called the Binet and Rai systems. the care team will probably need to draw a biopsy where cells are removed and then reviewed for the presence of cancer. The scans may be able to report where the cancer is, but by looking at these cells individually, they tell them how rapidly the cells will likely grow or what grade they are.

Staging is different from grading and is done for most, but not all, cancers.

Tumors generally tend to be low, intermediate, or high grade. Low-grade tumors look similar to normal cells and grow slowly. High-grade tumors look very different from normal cells and grow quickly.

Tumor grades generally range from G1, or low, to G4, or high, but sometimes grading systems are used only with certain cancers, so it’s always good to ask the care team for answers as you go along.

The grade of the cancer your patient has is a component in how the cancer care team stages the cancer and determines the patient’s prognosis, or outlook.

CNS cancers are graded, not staged. Far more than cancer that starts in the brain or spinal column, brain and spinal column cancers occur when a tumor located somewhere else inside the body spreads to the CNS.

Why is Early Detection and Diagnosis Important?

Though the disease may advance aggressively, stage 4 cancer is mostly diagnosed at a late stage. The cancer would be detected at its early stages is very crucial for better prognosis and treatment. In some cases, treatments at early stages may end the progression of the cancer to stage 4. Regular screening, awareness of symptoms, and genetic testing are vital in detecting cancers early to increase good outcomes.

These patients who are already diagnosed with stage 4 cancer highly require a proper and accurate diagnosis of how far the cancer has gone, which may go a long way in formulating the appropriate treatment plan.

Other tests to be carried out include CT scans, MRIs, PET scans, and biopsy procedures to confirm the spread and determine the need for treatment.

Stage 4 Cancer Treatment in India:

There is no fixed treatment for stage 4 cancer. Instead, it will depend on many considerations that include factors such as the type of cancer and genetic mutations involved, the age and general health of the patient, and even treatment preferences. Dr. Vikesh Shah best cancer Immunotherapy in Ahmedabad with extensive experience and offers diverse treatments in India for stage 4 cancer with conventional therapies as well as modern state-of-the-art treatments to control it.

  • Hormone therapy
  • Targeted therapy
  • Chemotherapy
  • Immunotherapy


Immunotherapy in India is one of the new paradigms of anticancer treatment; it works on strengthening the body’s immune system to combat cancers. Immunotherapy drugs can make the immune system in the body realize that it is severely damaging and killing cancerous cells. Immunotherapy works extremely well in stage 4 cancers, such as melanoma and lung cancer. Dr. Vikesh Shah may often suggest immunotherapy along with other treatments for further improvement.

Stage 4 cancer treatment

Stage 4 Treatment of metastatic breast cancer

For cancer that has spread from the breast and nearby lymph nodes, the treatments are typically systemic drug therapies. They are as follows:

  • Hormone therapy
  • Targeted drugs
  • Chemotherapy
  • Immunotherapy

They may be used alone or in combination and may be selected based on the hormone receptor as well as the HER2 status of the cancer.

Surgery and radiation can provide relief from symptoms caused by a tumor that is growing but do not remove the cancer. For example, doctors might do surgery to remove the tumor or use radiation to make the tumor smaller if it:

  • Is blocking a blood vessel
  • Is causing an ulcer
  • Is pressing on the spinal cord

Find out about breast cancer treatment

Stage 4 Lung Cancer Treatment

Normally, stage 4 lung cancer also receives systemic drug therapies.

Stage IV lung cancer that has spread to only one distant area tends to be treated differently than more widely spread lung cancer. The focus of treatment for cancers at this stage is often more on the site to which the cancer has spread.

Surgery and/or radiation may also be used to remove the cancer altogether from the distant site. Treatment from that point may then be directed at the primary site of the cancer in the lung and may take the form of chemotherapy, surgery radiation, or some combination of these treatments.

There is more often widely spread stage 4 lung cancer; this is also termed stage 4B. Considering the numerous gene mutations linked to the development of lung cancer, genetic testing can probably be the first treatment.

If there is a genetic mutation responsible for the patient’s lung cancer, this may be treated with the use of a targeted drug focusing on that exact mutation. Immunotherapy may be given to patients.

Treatment of stage 4 prostate cancer

This type of cancer is usually treated with systemic drug therapy and/or radiation therapy. Treatment options may include:

  • Hormone therapy
  • Hormone therapy in combination with chemotherapy
  • Radiation therapy that is done followed by, or without hormone therapy

Symptoms can also be relieved with surgery and/or radiation; for example, when the tumor is interfering with a patient’s urination or causing bleeding. Treatment for bone metastases from prostate cancer may include treatments aimed simply at symptoms, such as drugs that strengthen bones or radiation aimed at bone-dwelling cancer.

For some men, particularly those of older age or with serious concomitant health issues, observation or watchful waiting may be the most appropriate treatment even at stage 4. 

Treatment of stage 4 colorectal cancer

It can also be treated with surgery when the cancer has spread to very few small areas in the lungs and/or liver. Chemotherapy would then follow surgery.

For tumors that have spread to more sites, or where surgery is not able to remove them, chemotherapy may be given first, to shrink tumors. If they have shrunk enough, it may then be possible for the care team to remove them with surgery, with the patient having more chemotherapy after surgery.

Stage 4 diffuse colon cancer

The primary treatments would include chemotherapy and/or targeted therapies. Symptom management surgery may be recommended by the care team if the tumor is causing symptoms or exerting pressure on other organs in that body region to help alleviate the symptoms.

For cancers that have spread to only a few, very distinct areas in the liver or lungs, different combinations of chemotherapy, radiation, and surgery may be employed to try to shrink and remove the cancer. After surgery, the patient will likely receive chemotherapy and/or radiation as adjuvant treatment.

 

Survival Rate and Prognosis of Stage 4 Cancer

Although the prognosis of stage 4 cancers is variable since it depends on the type of tumor, the extent it has spread, and the patient’s reaction to treatment, survival rates may be lower at this stage. Many patients survive into old age after the treatment. The advancement in therapies for stage 4 cancer.


Improvement in therapies and the past two years concerning treatments of cancer with better results for a patient diagnosed with stage 4 cancer; this includes targeted treatments, immunotherapy, and palliative care that sustain the life expectancy and quality of a patient during such a condition.

Support to patients with a diagnosis of cancer stage 4

Beyond the medical treatment for cancer, emotional and psychological support becomes decidedly essential for a stage 4 cancer patient. Dr. Vikesh Shah understands how traumatic the cancer diagnosis and subsequent treatment may be on an individual’s psychology, and so keeps himself updated with all the various support groups that ensure patients and families benefit from all the support needed in this cancer journey.

Indeed, one of the hardest diagnoses that any patient faces is stage IV, but with the help of expertise through Dr. Vikesh Shah, patients in India can now receive comprehensive treatment that is outlined for them and works especially for their needs. They can visit Ahmedabad to his clinic for better treatment and guidance.

Fourth-stage cancer: for experienced treatment and advanced treatment options, contact Dr. Vikesh Shah’s clinic today in Ahmedabad. Patients can survive the journey with dignity and hope through proper treatment and support.

Conclusion

While, by any stretch of the imagination, a last-stage cancer diagnosis can’t be anything but difficult, developments in medical science and good treatment options available in India breed hope for many. So, whether it’s chemotherapy, radiation, immunotherapy, or palliative care, patients in India are given great choices in therapies that take care of various symptoms to ensure quality of life.

Dr. Vikesh Shah is among the best immunotherapy cancer doctors in India for patient care while navigating the complexities of cancer treatment due to being a caring and professional oncologist. Coming to India for last-stage cancer treatment could give patients an option for quality medical treatment combined with affordability and personalized treatment plans that could make a difference in their battle against the sickness.

If you or a loved one need guidance or treatment for last-stage cancer, don’t hesitate to reach out to Dr. Vikesh Shah for a consultation. He can make this difficult time hopeful and confident in light of his expertise and the latest advancements in cancer care.